Parasitoid virus-like particles destroy Drosophila cellular immunity.
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منابع مشابه
Parasitoid virus-like particles destroy Drosophila cellular immunity.
Parasitoid wasps must avoid the destructive effects of the host's cellular defense system in order to exploit the host hemocoel as a suitable environment for their survival. To protect their eggs from encapsulation by Drosophila melanogaster blood cells, Leptopilina heterotoma females inject a factor that selectively destroys lamellocytes, the type of Drosophila blood cell involved in recogniti...
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L. heterotoma females inject VLPs along with their eggs into the hemocoel of the Drosophila larva. The VLPs destroy lamellocytes that are potentially harmful for the parasite eggs, but the other types of host hemocytes retain their functions. The parasitized third instar Drosophila larvae continue to grow and pupariate, showing no outward adverse effects. Minimum disruption to the growth and de...
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In Drosophila melanogaster larvae, three classes of circulating cellular immune surveillance cells (hemocytes) can be identified: plasmatocytes, crystal cells, and lamellocytes. Plasmatocytes are professional phagocytes most similar to the mammalian monocyte/macrophage lineage and make up approximately 95% of circulating hemocytes. The other approximately 5% of circulating hemocytes consists of...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1990
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.87.21.8388